Interactive Demo
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🧬
Welcome to the Geneius Demo
Walk through the complete Geneius experience — from DNA upload to personalized report — with pre-filled sample data. No real genetic data needed.
📤
Upload
See the DNA file upload experience
🧪
Health Wizard
Pre-filled health profile intake
🔬
Gene Console
Interactive variant explorer
📊
Full Report
Complete analysis report & AI chat
Demo uses sample data for Sarah Mitchell, age 34
Step 1 of 6
📤 DNA File Upload
Customers upload their raw DNA data from 23andMe, AncestryDNA, VCF files, or even PDF lab reports. The system auto-detects the format and begins processing.
📂
sarah_mitchell_23andme.txt
23andMe Raw Data · 12.4 MB · Detected format automatically
Ready to process
✅ Supported Formats
23andMe AncestryDNA VCF Nebula MyHeritage PDF Lab Reports DOCX Photo / AI Vision
614K
SNPs Parsed
47
Variants Found
8
Homozygous
39
Heterozygous
Step 2 of 6
🧪 Health Wizard
Customers complete a guided health intake — basics, conditions, medications, supplements, labs, lifestyle, and goals. Hypatia voice chat can fill it out via conversation. Everything below is pre-filled for the demo.
1
Basic Info
✅
Name
Sarah Mitchell
Age
34
Sex
Female
Height / Weight
5'6" · 138 lbs
Ethnicity
Caucasian / Northern European
Blood Type
O+
2
Medical Conditions
✅
Hashimoto's Thyroiditis Anxiety (managed) Iron Deficiency — Resolved No Cardiovascular Issues
3
Medications
✅
Current Rx
Levothyroxine 75mcg (daily)
As Needed
Lorazepam 0.5mg (PRN anxiety)
4
Current Supplements
✅
Vitamin D3 5000 IU Magnesium Glycinate 400mg Omega-3 Fish Oil 2g Selenium 200mcg Methylfolate 800mcg
5
Lab Results
✅
TSH
2.4 mIU/L Normal
Free T4
1.1 ng/dL Normal
Vitamin D
38 ng/mL Optimal
Homocysteine
11.2 μmol/L Slightly High
Ferritin
42 ng/mL Normal
hs-CRP
1.8 mg/L Borderline
6
Lifestyle
✅
Exercise
3-4x/week — Yoga, HIIT, Walking
Diet
Mediterranean-leaning, Gluten-light
Sleep
6.5–7 hrs avg · Occasional insomnia
Stress Level
Moderate (5/10)
7
Goals
✅
Optimize Thyroid Function Improve Methylation Reduce Inflammation Better Sleep Energy Optimization
Step 3 of 6
🔬 Gene Console — Dashboard
After processing, customers land on their Gene Console dashboard — a high-level overview of all analyzed clusters, variant counts, and genetic scores.
47
Total Variants
8
Homozygous
39
Heterozygous
12
Guideline-Level
18
Moderate Evidence
82
Optimization Score
🧬 Cluster Overview
🧪Methylation67
5 variants · 2 homozygous
💊Pharmacogenomics88
6 variants · 1 homozygous
🛡️Detox / Oxidative79
7 variants · 1 homozygous
🧠Neurotransmitters74
8 variants · 2 homozygous
🦴Bone & Vitamin D91
4 variants · 0 homozygous
❤️Cardiovascular85
5 variants · 1 homozygous
Step 4 of 6
🧬 Gene Console — Variant Explorer
Each variant is displayed as a card with gene name, rsID, genotype, evidence tier, domain category, and linked supplement/peptide recommendations. Customers can click to expand full details.
All (47) Methylation (5) Pharmacogenomics (6) Detox (7) Neuro (8) Cardiovascular (5)
MTHFR
rs1801133 · C677T
HOM C/C→T/T
Methylenetetrahydrofolate reductase — reduced folate metabolism, elevated homocysteine risk
Methylation Guideline
Methylfolate 800mcg Riboflavin 50mg B12 (methylcobalamin)
COMT
rs4680 · Val158Met
HET A/G
Catechol-O-methyltransferase — intermediate dopamine/norepinephrine metabolism
Neuro Moderate
Magnesium SAMe (caution)
CYP2D6
rs3892097 · *4 allele
HET
Cytochrome P450 2D6 — intermediate metabolizer, affects codeine, SSRIs, tamoxifen
Pharmacogenomics Guideline
APOE
rs429358 · ε3/ε3
NORMAL
Apolipoprotein E — normal lipid metabolism, no elevated Alzheimer's risk allele
Cardiovascular Guideline
VDR
rs1544410 · BsmI
HET
Vitamin D receptor — reduced receptor sensitivity, may need higher vitamin D intake
Bone & Vitamin D Moderate
Vitamin D3 5000 IU Vitamin K2 MK-7
SOD2
rs4880 · Ala16Val
HOM T/T
Superoxide dismutase 2 — reduced mitochondrial antioxidant defense
Detox Moderate
MitoQ / CoQ10 NAC 600mg BPC-157 250mcg
Showing 6 of 47 variants · Full console has search, filters, domain pills, and expandable detail drawers
Step 5 of 6
📊 Full Genetic Report
The generated report combines genetic analysis, health wizard data, lab results, and AI insights into a comprehensive document. Customers receive a shareable link with a unique token.
✅ Report Generated Token: gx_demo_sarah_mitchell_2026 · 47 variants · Generated May 30, 2026

🧬 Genetic Analysis Report — Sarah Mitchell

Generated May 30, 2026 · 47 variants analyzed · Geneius AI v2.1

Executive Summary

Sarah presents a genetic profile with notable methylation pathway variants (MTHFR C677T homozygous) that explain her slightly elevated homocysteine levels (11.2 μmol/L). Combined with her Hashimoto's thyroiditis and COMT intermediate metabolizer status, a targeted supplementation strategy focusing on methylated B-vitamins, antioxidant support, and thyroid cofactors is recommended.

🧪 Methylation Panel

MTHFR C677T (rs1801133) — Homozygous T/T

This is the most clinically significant finding. Homozygous T/T reduces MTHFR enzyme activity by approximately 70%, impairing folate metabolism and methylation capacity. This directly correlates with Sarah's borderline homocysteine of 11.2 μmol/L.

  • Recommendation: Continue methylfolate 800mcg (already taking ✅)
  • Add: Riboflavin (B2) 50mg/day — cofactor for MTHFR enzyme
  • Add: Methylcobalamin (B12) 1000mcg sublingual
  • Monitor: Recheck homocysteine in 8–12 weeks

MTHFR A1298C (rs1801131) — Heterozygous A/C

Compound heterozygosity with C677T modestly amplifies the methylation impairment. Current supplement stack addresses this adequately.

💊 Pharmacogenomics

CYP2D6 *4 (rs3892097) — Intermediate Metabolizer

Sarah is an intermediate metabolizer for CYP2D6 substrates. This affects metabolism of her PRN lorazepam (minimal CYP2D6 involvement — low concern) but is important for future prescribing decisions.

  • Drug interactions to flag: Codeine (reduced activation), some SSRIs, tamoxifen
  • Action: Share this finding with prescribing physician

🧠 Neurotransmitter Profile

COMT Val158Met (rs4680) — Heterozygous

Intermediate dopamine/norepinephrine clearance. This is consistent with Sarah's managed anxiety — she may be more sensitive to catecholamine fluctuations under stress but has balanced baseline metabolism.

  • Lifestyle: Stress management practices (yoga — already doing ✅)
  • Supplements: Magnesium glycinate (already taking ✅), consider L-theanine 200mg for acute stress

🛡️ Detox & Antioxidant

SOD2 Ala16Val (rs4880) — Homozygous T/T

Reduced mitochondrial superoxide dismutase activity increases oxidative stress burden. Combined with Hashimoto's (autoimmune-driven inflammation), targeted antioxidant support is strongly recommended.

  • Add: CoQ10 (ubiquinol) 200mg/day or MitoQ
  • Add: NAC 600mg 2x/day (glutathione precursor)
  • Consider: BPC-157 250mcg subcutaneous (gut-thyroid axis support, emerging evidence)

📋 Consolidated Supplement Protocol

Morning (with food)
  • Methylfolate 800mcg ✅ (continuing)
  • Methylcobalamin (B12) 1000mcg sublingual NEW
  • Riboflavin (B2) 50mg NEW
  • Vitamin D3 5000 IU ✅ (continuing)
  • Omega-3 Fish Oil 2g ✅ (continuing)
  • Selenium 200mcg ✅ (continuing)
Evening
  • Magnesium Glycinate 400mg ✅ (continuing)
  • CoQ10 (ubiquinol) 200mg NEW
  • NAC 600mg NEW
  • Vitamin K2 MK-7 100mcg NEW
Peptide Protocol (optional, discuss with provider)
  • BPC-157 250mcg SC daily × 4 weeks PEPTIDE

⚠️ Important Disclaimers

This report is for educational and informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before starting, stopping, or modifying any supplement, medication, or health protocol. Genetic variants are one factor among many — environmental, lifestyle, and clinical context must be considered. Geneius uses peer-reviewed research and clinical guidelines but cannot guarantee outcomes.

Step 6 of 6
🎓 Ed the Educator & Report Sharing
Customers can ask plain-language questions about their variants using Ed the Educator — an AI chat widget grounded in their actual genetic data. Reports are shared via unique token links.
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Ed the Educator
Ask anything about your variants — in plain language
🎓 Hi Sarah! I can help you understand any of the 47 variants in your report. Try asking things like "What does my MTHFR result mean?" or "Why is CoQ10 recommended?"
What does it mean that my MTHFR is homozygous?
🎓 Great question! Your MTHFR C677T result is homozygous T/T, meaning you have two copies of the variant. This reduces your MTHFR enzyme activity by about 70%, which makes it harder for your body to convert folic acid into its active form (methylfolate).

That's why your report recommends methylfolate instead of regular folic acid — your body can use it directly without needing the MTHFR enzyme. The good news? You're already taking methylfolate 800mcg, which is exactly right! 💚
Should I be worried about my homocysteine level?
🎓 Your homocysteine is 11.2 μmol/L — it's slightly above optimal (ideal is under 10) but not in a danger zone. Given your MTHFR status, this is expected and very manageable.

The report recommends adding Riboflavin (B2) 50mg and Methylcobalamin (B12) 1000mcg — these are cofactors that help the methylation pathway work better even with reduced MTHFR activity. With those additions, we'd expect your homocysteine to drop into the optimal range within 8–12 weeks. Your provider can recheck it then. 📊
Demo mode — chat is read-only. Live customers get unlimited Q&A grounded in their actual data.
🔗 Report Sharing
Shareable Link
https://geneius.net/report.html?token=gx_demo_sarah_mitchell_2026
Features
Token-gated Access No Login Required Ed Chat Included Email Delivery
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Demo Complete!
You've seen the full Geneius experience — from DNA upload to AI-powered report generation. Ready to get started with a real account?
← Back to Admin Console 🧬 Open Gene Console
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